In Parkinson's disease, what is the primary neurotransmitter that is deficient?

In Parkinson's disease, the primary neurotransmitter that is deficient is dopamine. This deficiency occurs due to the degeneration of dopamine-producing neurons in a specific area of the brain called the substantia nigra. Dopamine is crucial for the regulation of movement and coordination. When levels drop, it leads to the characteristic symptoms of Parkinson's, such as tremors, rigidity, and bradykinesia (slowness of movement).

Understanding the role of dopamine in the pathophysiology of Parkinson's disease is important for music therapists, as it informs their approach in using music and rhythmic interventions to help manage motor and non-motor symptoms in individuals with this condition. Through rhythmic auditory stimuli, for instance, music therapy can help in cueing movements and improving motor functions in patients suffering from the dopamine deficiency associated with Parkinson's disease.